即使是中度日常活动也可以降低妇女死亡风险


  【24drs.com】根据11月2日在线发表于美国预防医学期刊的一篇研究,即使是一天内的合理轻度活动量,也与妇女的任何原因死亡风险降低有关。男性可以从依照建议的中度到重度运动(moderate to vigorous physical activity,MVPA)中降低风险,但是不能单靠轻度活动。
  
  这些发现来自客观测量的活动程度,而这通常比常用的自我报告更可靠,因为自我报告受到回忆偏差和社会期望偏差的影响。
  
  加拿大安大略Kingston皇后大学Ian Janssen博士以及Emily Borgundvaag写道,相较于只有适量运动者,运动量少或没有MVPA者的死亡率风险有差异;相较于做许多运动者,有适量MVPA者之风险小或者没有差异。
  
  他们写道,从行为改变的角度来看,MVPA和死亡率风险的剂量反应模式是鼓舞人心的,给不运动成年人的建议不是需要去跑马拉松,而是只要做一点点MVPA。
  
  研究人员使用Actigraph加速度计测量5,562名成年人的运动,测量期间4-7天,这5千多名成年人参加了2003-2006年的美国国家健康与营养调查研究,研究开始时的平均年龄为48.4岁,之后追踪平均6.7年。
  
  研究者依据每日轻度身体活动量(LPA)及MVPA量将参与者分成5组,他们将第一个五分之一定义为低参与组—包括每天10.0 - 157.0分钟的LPA到最多每天3.1分钟的MVPA;中度到高度的五分之一的活动量范围为每天157.1 - 423.4分钟的LPA以及每天3.2 - 343.8分钟的MVPA。
  
  校正年龄、性别、种族、社经状态、饮食、抽菸、饮酒等因素之后,他们发现,相较于低参与组,中度到高度LPA的女性死于任何原因的风险降低42%(风险比[HR]为0.58; 95%信赖区间[CI]为0.38 - 0.88)。
  
  此外,中度到高度的五分之一中,中度到强度运动之女性的所有原因死亡率风险降低66%(HR, 0.34; 95% CI, 0.20 - 0.57)。
  
  研究者接著比较了不同运动程度的妇女,以及只有低度LPA 和低度MVPA的妇女,他们发现,即便只是增加中度的MVPA量也可增添最大效益:如果他们是LPA最低五分之一组者,死亡率降低84% (HR, 0.16; 95% CI, 0.07 - 0.34) ,如果他们是中度到高度的LPA,则是降低83%(HR, 0.17; 95% CI, 0.09 - 0.36)。
  
  然而,即使是低度MVPA的妇女,如果他们的LPA程度为中度到高度,其死亡率风险降低58% (HR, 0.42; 95% CI, 0.26 - 0.70)。
  
  同时,男性在所有原因死亡率与LPA之间并无统计上的显著差异(HR, 1.02; 95% CI, 0.64 - 1.61),他们也指出,在中度到高度的五分之一,MVPA降低61%的各种原因死亡率(HR, 0.39; 95% CI, 0.27 - 0.56),但是,低度MVPA者并未从高度LPA中获得降低死亡率风险的效益。
  
  作者们写道,在本研究中,第二个五分之一的MVPA者累计有每周23-69分钟的MVPA,并非全部都符合标准,大多数是中度活动。85%的MVPA是零星累积的(例如:在这里、在那里各几分钟),而不是至少10分钟时间的MVPA。
  
  资料来源:http://www.24drs.com/
  
  Native link:Even Modest Daily Activity May Reduce Mortality Risk for Women

Even Modest Daily Activity May Reduce Mortality Risk for Women

By Tara Haelle
Medscape Medical News

Even a reasonable amount of light physical activity spread throughout the day is linked to a reduction in women's risk for death from any cause, according to a study published online November 2 in the American Journal of Preventive Medicine. Men had a reduced risk from moderate to vigorous physical activity (MVPA), as recommended daily, but not from light physical activity alone.

These findings come from objectively measured activity levels that are generally more reliable than commonly used self-reporting, which is subject to recall bias and social desirability bias.

"[A]lthough mortality risk differs in those who do little or no MVPA versus those who did only a modest amount, there is little or no difference in risk in those who do a modest amount of MVPA versus those who do a lot," write Emily Borgundvaag, MSc, and Ian Janssen, PhD, from Queen's University in Kingston, Ontario, Canada.

"The dose–response pattern between MVPA and mortality risk is encouraging from a behavior change standpoint," they write. "The message for inactive adults does not need to be to run a marathon, but rather to just do a little bit of MVPA."

The researchers used Actigraph accelerometers to measure the physical activity of 5562 adults, over the course of 4 to 7 days. The adults, who were participants in the 2003 to 2006 National Health and Nutrition Examination Survey and had an average baseline age of 48.4 years, were then tracked for a mean 6.7 years.

The investigators stratified participants into quintiles on the basis of their amount of daily light physical activity (LPA) and their amount of MVPA. They designated the first quintile as low participation, which included 10.0 to 157.0 minutes daily of LPA and up to 3.1 minutes daily of MVPA. Modest to high quintiles of activity ranged from 157.1 to 423.4 minutes per day for LPA and 3.2 to 343.8 minutes daily of MVPA.

After adjusting for age, sex, race, socioeconomic status, diet, smoking, and alcohol consumption, they found that women with modest to high levels of LPA were 42% less likely to die from any cause (hazard ratio [HR], 0.58; 95% confidence interval [CI], 0.38 - 0.88) than those in the low participation group.

In addition, women with moderate to vigorous physical activity in the modest to high quintiles had a 66% lower risk for all-cause mortality (HR, 0.34; 95% CI, 0.20 - 0.57).

The researchers then compared women with different combinations of activity levels with women with only low LPA and low MVPA. They found that adding even a modest amount of MVPA added the greatest benefit: an 84% (HR, 0.16; 95% CI, 0.07 - 0.34) reduction in mortality if they were in the lowest quintile for LPA and 83% reduction if they had modest to high levels of LPA (HR, 0.17; 95% CI, 0.09 - 0.36).

Yet even women with low levels of MVPA had a 58% lower risk for mortality if their LPA levels were modest to high (HR, 0.42; 95% CI, 0.26 - 0.70).

Men, meanwhile, did not have a statistically significant difference in all-cause mortality with LPA (HR, 1.02; 95% CI, 0.64 - 1.61). They did show a 61% (HR, 0.39; 95% CI, 0.27 - 0.56) decreased likelihood of all-cause mortality with MVPA in the modest to high quintiles, but those with low levels of MVPA did not gain any reduction in mortality risk with high levels of LPA.

"In the present study, participants in the second MVPA quintile accumulated 23–69 minutes/week of MVPA, a modest amount of activity by most if not all standards," the authors write. "Eighty-five percent of this MVPA was accumulated sporadically (e.g., a couple of minutes here and there) and not in bouts of MVPA that were at least 10 minutes long."

The research was funded by a Canada Research Chair award. The authors have disclosed no relevant financial relationships.

Am J Prev Med. Published online November 2, 2016.

    
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