饮用玛黛茶与骨密度较高有关


【24drs.com】2012年1月的Bone期刊中,阿根廷骨质疏松预防与治疗计画的Andrea Conforti医师等人报告指出,停经后妇女饮用玛黛茶(Ilex paraguariensis)者,和没有喝该种饮品者相比,骨密度(BMD)值较高。
  
  玛黛茶是风行于南美洲、一种含有黄嘌呤的饮料,它可制为茶叶以热水冲泡后过滤饮用。更普遍的是,将茶叶放在一个乾葫芦中、以热水反覆冲泡、用一个金属吸管饮用,本研究的研究对象即使用此方法。这种饮用方法,所含的咖啡因含量可达约330 mg/L。
  
  这篇跨世代观察型研究中,研究者探讨了该骨质疏松计画中,每天饮用玛黛茶至少1 L、至少5年的停经后妇女(n = 146人),并根据年纪及停经时间与没有喝这种茶饮的妇女配对。两组都属于久坐类型,定义为没有进行运动计画。
  
  两组在年纪、停经后时间、身高、体重、热量摄取都进行配对,不过,喝茶组的身体质量指数比没有喝茶组多1.1 kg/m2。
  
  目前有抽菸或者以前曾抽菸者、每周喝酒超过50 g的妇女、目前有接受荷尔蒙替代治疗者、接受双磷酸盐类治疗超过6个月者、接受长期皮质类固醇治疗者都被排除。
  
  由不知道每个研究对象饮用玛黛茶状态的研究者分析所有BMD测量参数。
  
  使用双能量X光吸收仪(DXA)测量BMD,研究者发现,喝茶者的腰椎BMD比没有喝茶者多9.7%(分别是0.952 g/cm2和0.858 g/cm2;P < .0001),股骨颈的BMD则是多6.2%(分别是0.817 g/cm2和0.776 g/cm2;P = .0002)。研究者进行多重回归分析后发现,除了身体质量指数,在这些地区,饮用玛黛茶是唯一与BMD显著相关的变项(P = .0028)。
  
  与对照组相比,虽然各年龄层的玛黛茶组有比较高的腰椎和股骨颈BMD,两组的BMD-年纪回归线斜率并无差异,表示喝茶者和对照组随时间流失的BMD相似。
  
  进行DXA扫描时,两组的低影响骨折数相似(喝茶组13例、对照组17例;P = .5637)。
  
  作者们结论表示,长期饮用玛黛茶与腰椎及股骨颈BMD较高有关,认为这种茶饮对停经后妇女的骨密度有正面帮助,他们也指出,根据其它研究者以前所提「咖啡因对BMD有害的报告」、有关饮用玛黛茶的假设应被排除。
  
  研究限制是,回溯设计的本质、研究对象自我报告饮用玛黛茶的情况、研究对象是参与骨质疏松预防诊断与治疗之计划对象,研究结果无法一般化到年轻的妇女、男性或孩童。
  
  资料来源:http://www.24drs.com/professional/list/content.asp?x_idno=6703&x_classno=0&x_chkdelpoint=Y
  

Higher Bone Mineral Density Related to Drinking Yerba Mate

By Daniel M. Keller, PhD
Medscape Medical News

January 2, 2012 — Postmenopausal women who consumed yerba mate (Ilex paraguariensis) tea had higher bone mineral density (BMD) compared with women who did not drink the tea, Andrea Conforti, MD, from the Program for the Prevention and Treatment of Osteoporosis in Mendoza, Argentina, and colleagues report in the January 2012 issue of Bone.

Yerba mate is a xanthine-containing beverage that is popular in South America. It may be prepared as an infusion of dried leaves steeped in hot water and then filtered. More commonly, it is consumed through a metal straw inserted into a dried gourd containing the leaves, over which hot water is poured repeatedly, and it was these users who were included in the study. By this method, the tea contains caffeine at a concentration of about 330 mg/L.

In this cross-sectional, observational study, investigators identified postmenopausal women in the osteoporosis program who drank at least 1 L of yerba mate tea daily for at least 5 years (n = 146) and matched them by age and time since menopause with an equal number of women who did not drink yerba mate tea. Both groups were fairly sedentary, defined as not being in a program of physical exercise.

The 2 groups were well matched for age, time since menopause, height, body mass, and calcium intake. However, the tea drinkers had a body mass index 1.1 kg/m2 greater than the nondrinkers.

Current or former cigarette smokers, women who consumed more than 50 g of alcohol per week, those currently receiving hormone replacement therapy, those who had received bisphosphonate treatment for more than 6 months, or those who received chronic corticosteroid treatment were excluded.

One of the investigators, who was blinded to the yerba mate drinking status of each participant, performed the analysis of all the BMD measurements.

Measuring BMD by dual-energy X-ray absorptiometry (DXA), the researchers found that the tea drinkers had 9.7% greater lumbar spine BMD compared with non–tea drinkers (0.952 g/cm2 vs 0.858 g/cm2, respectively; P < .0001), as well as 6.2% greater femoral neck BMD (0.817 g/cm2 vs 0.776 g/cm2, respectively; P = .0002). By a multiple regression analysis, the researchers found that in addition to body mass index, drinking yerba mate tea was the only variable that significantly correlated with BMD at these sites (P = .0028).

Although the yerba mate group had higher lumbar spine and femoral neck BMD at all ages compared with control patients, the slopes of the regression lines for BMD vs age did not differ between the groups, indicating that loss of BMD over time was similar for the tea-drinkers and the control participants.

At the time of DXA scanning, the number of low-impact bone fractures was similar between the groups (13 for tea drinkers and 17 for control patients; P = .5637).

The authors conclude that chronic consumption of yerba mate tea was associated with greater BMD at the lumbar spine and femoral neck, "suggesting a protective effect of this tea on bone mass of postmenopausal women." They also note that their earlier hypothesis that yerba mate consumption, based on other investigators' reports of a deleterious effect of caffeine on BMD, "should be rejected."

Limitations of the study are its retrospective nature, participants' self-reports of yerba mate consumption, and that the study participants were a selected population of postmenopausal women in a program for the prevention, diagnosis, and treatment of osteoporosis. Results may not be generalizable to younger women, men, or children.

The study was supported by Obra Social de Empleados Publicos, Mendoza, Argentina. The authors have disclosed no relevant financial relationships.

Bone. 2012;50:9-13.

    
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