40多岁成人的代谢症候群与16岁时看电视及运动习惯有关


  【24drs.com】根据这项主题首次发表的一篇前瞻研究,16岁时看电视和休闲运动的习惯可预测43岁时的代谢症候群。
  
  瑞典Umea大学Patrik Wennberg博士等人在1月22日糖尿病照护期刊在线发表该篇文献,对于看电视和后续代谢风险,这篇研究支持之前的研究结果,且提供了新证据指出,这个关联在生命周期的影响期间相当长:从青春期到中年。
  
  研究者也相信,有不同的机转影响看电视和运动习惯的关联,因为这些活动和不同的代谢症候群因素有关。
  
  然而,他们指出,这些结果认为,青少年时少看电视、加上规律运动,或许可促成长大后的心脏代谢健康。
  
  针对北瑞典以人口为基础的一个世代、采用自我评估问卷评估16岁时看电视和休闲运动的习惯。依据国际糖尿病联合会(IDF)规范,有888个参与者(原始样本数的82%)在43岁时确认有代谢症候群,定义是女性腰围大于等于80公分,男性大于等于94公分,且下列准则有两项以上:
  * 三酸甘油脂增加(1.7 mmol/L或以上)或有接受脂质异常之治疗。
  * 高密度脂蛋白(HDL)胆固醇降低(小于1.29 mmol/L(女性)或小于1.03 mmol/L(男性))或有接受脂质异常之治疗。
  * 血压上升(收缩压130 mm Hg或以上、舒张压85 mm Hg或以上)或有进行高血压治疗。
  * 空腹血糖值上升(5.6 mmol/L或以上)或有第2型糖尿病诊断。
  
  26.9%的参与者被发现有代谢症候群;表示在16岁时一天看多部电视节目者,在43岁时患有代谢症候群的比率,是每周看一个节目或更少者的2倍之多(校正胜算比[OR],2.14);同样地,表示每月只有数次休闲运动者,比那些在青少年时期每天都有休闲运动者更可能在成年时患有代谢症候群(OR,2.31)。
  
  Wennberg博士等人的结果认为,看电视和休闲运动与后续的心脏代谢风险都有所谓剂量反应的关联。
  
  16岁时的看电视习惯与43岁时的腹部肥胖、HDL胆固醇低、高血压有关。青少年时的休闲运动少者,与成年时腹部肥胖及三酸甘油脂上升有关。作者们表示,这些观察发现认为,看电视/久坐和运动与后续之代谢风险的关联,可藉由不同的心脏代谢路径调控。
  
  他们指出,这意味著需针对久坐行为,如看电视、或增加休闲运动等进行不同的介入策略。
  
  作者们结论指出,青少年时少看电视、青少年和成年时都要有规律的休闲运动,可促成后来的心脏代谢健康。
  
  资料来源:http://www.24drs.com/professional/list/content.asp?x_idno=6980&x_classno=0&x_chkdelpoint=Y
  

Metabolic Syndrome in 40s Linked to TV, Exercise at Age 16

By Lisa Nainggolan
Medscape Medical News

Television viewing habits and leisure-time physical activity at the age of 16 years independently predicts the metabolic syndrome at age 43, according to the first prospective study to examine this.

The work "supports previous findings" and, for TV viewing and subsequent metabolic risk, "provides new evidence that this association may stretch over a considerable proportion of the lifespan: from adolescence to mid-adulthood," say Patrik Wennberg, PhD, from Umea University, Sweden, and colleagues in their article published online January 22 in Diabetes Care.

The researchers also believe that separate mechanisms may be at play here for TV-viewing and physical-activity habits, because these activities were linked to different metabolic-syndrome components.

Nevertheless, the findings "suggest that reduced TV viewing in adolescence, in addition to regular physical activity, may contribute to cardiometabolic health later in life," they state.

More TV, Less Exercise Doubled Metabolic Syndrome

TV viewing habits and leisure-time physical activity at age 16 years were assessed by self-administered questionnaires in a population-based cohort in Northern Sweden. The presence of the metabolic syndrome at age 43 years was ascertained in 888 participants (82% of the baseline sample) using the International Diabetes Federation (IDF) criteria, defined as a waist circumference 80 cm or greater for women and 94 cm or greater for men and 2 or more of the following criteria:

  • Increased triglycerides (1.7 mmol/L or greater) or specific treatment for that lipid abnormality.

  • Reduced high-density lipoprotein (HDL) cholesterol (less than 1.29 mmol/L for women and less than 1.03 mmol/L for men) or specific treatment for that lipid abnormality.

  • Increased blood pressure (systolic BP 130 mm Hg or greater or diastolic 85 mm Hg or greater) or treatment of hypertension.

  • Increased fasting glucose (5.6 mmol/L or greater) or diagnosed type 2 diabetes.

Metabolic syndrome was identified in 26.9% of participants. Those who reported "watching several [TV] shows a day" at 16 were twice as likely to have the metabolic syndrome at age 43 than those who said they watched "1 show/week" or less (adjusted odds ratio [OR], 2.14). Similarly, those who noted leisure-time physical activity "several times per month" were more likely to have metabolic syndrome later in life than those who reported "daily" leisure-time physical activity in their teens (OR, 2.31).

"Our results suggest a dose-response relationship for both TV viewing and leisure-time physical activity with subsequent cardiometabolic risk," write Dr. Wennberg and colleagues.

TV viewing at age 16 years was linked to central obesity, low HDL cholesterol, and hypertension at age 43 years. Low leisure-time physical activity in the teen years was associated with central obesity and raised triglycerides later in life. These observations suggest that associations between TV viewing/sedentary behavior and physical activity with subsequent metabolic risk may be mediated via different cardiometabolic pathways, the authors say.

This possibility means that "different strategies may need to be adopted" with regard to interventions targeting sedentary behavior, such as TV viewing, and those aiming to increase leisure-time physical activity, they note.

"Reduced TV viewing in adolescence, in addition to and independently of regular leisure-time physical activity in adolescence and adulthood, may contribute to cardiometabolic health later in life," the authors conclude.

The authors have disclosed no relevant financial relationships.

Diabetes Care. Published online January 22, 2013.

    
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